Looking Beyond CD Markers: How Cellular Morphology Is Opening a New Perspective in Leukemia Research
The treatment of chronic myeloid leukemia (CML) has advanced dramatically with the advent of tyrosine kinase inhibitors (TKIs). However, achieving a true functional cure remains far from straightforward. One of the major obstacles is the persistence of leukemic stem cells, which can remain in the body even after treatment. How can researchers identify these rare cell populations, clarify their properties, and ultimately find ways to eliminate them from the body? The research team led by Dr. Tomoiku Takaku and Dr. Kohjin Suzuki at the Department of Hematology, Juntendo University Graduate School of Medicine — now affiliated with the Department of Hematology at Saitama Medical University Hospital — has spent many […]
Evaluating Cell Function Through VC Cell Therapy’s Experience with VisionSort® in Regenerative Medicine
VCCT’s Challenge: Evaluating Cell Quality for Clinical Translation Guided by its vision, “Providing all solutions for all patients,” VC Cell Therapy Inc. (VCCT) is working to realize cell therapies for outer retinal diseases. At VCCT, Dr. Tomohiro Masuda leads manufacturing development and quality control, two functions central to the company’s R&D. To evaluate cell quality beyond conventional methods, Dr. Masuda introduced VisionSort®, a cell sorter equipped with ThinkCyte’s Ghost Cytometry® (hereafter GC) technology. For cellular products, evaluating and managing cell characteristics is essential when defining release criteria. For teams working from basic research through clinical-grade products, this remains a persistent R&D challenge. Even as two iPS-derived cellular products received their […]
